Recombinant Human Cathepsin D/CTSD (C-6His)
Product Sizes
10 µg
£612.00
32-7364-10UG
50 µg
£919.00
32-7364-50UG
About this Product
- SKU:
- 32-7364
- Extra Details:
- Source: Human Cells. MW :43.8kD. Recombinant Human Cathepsin D is produced by our Mammalian expression system and the target gene encoding Leu21-Leu412 is expressed with a 6His tag at the C-terminus. The protein acid protease active in intracellular protein breakdown and involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. It is specificity similar to; but narrower than; that of pepsin A and it does not cleave the 4-Gln-|-His-5 bond in B chain of insulin. It consists of a light chain and a heavy chain and expressed in the aorta extrcellular space. The Val-58 allele is significantly overrepresented in demented patients (11.8%) compared with non-demented controls (4.9%). Carriers of the Val-58 allele have a 3.1-fold increased risk for developing AD than non-carriers.It belongs to the peptidase A1 family
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
