Recombinant Human Intercellular Adhesion Molecule 1/ICAM-1/CD54 (C-6His)
Product Sizes
10 µg
£488.00
32-7297-10UG
50 µg
£636.00
32-7297-50UG
About this Product
- SKU:
- 32-7297
- Extra Details:
- Source: Human Cells. MW :50.54kD. Recombinant Human Intercellular Adhesion Molecule 1 is produced by our Mammalian expression system and the target gene encoding Gln28-Glu480 is expressed with a 6His tag at the C-terminus. Inter-Cellular Adhesion Molecule 1 (ICAM1) is a type of intercellular adhesion molecule continuously present in low concentrations in the membranes of leukocytes and endothelial cells. As an endothelial and leukocyte-associated transmembrane protein; ICAM1 is well known for its importance in stabilizing cell-cell interactions and facilitating leukocyte endothelial transmigration. The presence of heavy glycosylation and other structural characteristics lend ICAM1 binding sites for a number of immune-associated ligands. Notably; ICAM-1 binds to macrophage adhesion ligand-1 (Mac-1; ITGB2 / ITGAM); leukocyte function associated antigen-1 (LFA-1/integrin); and fibrinogen.ICAM-1 expressed by respiratory epithelial cells is also the binding site for rhinovirus; the causative agent of most common colds.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
