Recombinant Human Activin Receptor 2B/Activin RIIB/ACVR2B (C-6His)
Product Sizes
10 µg
£456.00
32-7280-10UG
50 µg
£562.00
32-7280-50UG
About this Product
- SKU:
- 32-7280
- Extra Details:
- Source: Human Cells. MW :14.37kD. Recombinant Human Activin Receptor IIB is produced by our Mammalian expression system and the target gene encoding Ser19-Thr134 is expressed with a 6His tag at the C-terminus. Activin proteins that belong to the transforming growth factor-beta (TGF- beta) superfamily; exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors. On ligand binding; type I and II receptors form a stable complex; resulting in phosphorylation of type I receptors by type II receptors with constitutive kinase activity; and subsequently initiates the activation of downstream molecules including the endogenous Smads. ActRIIB; also known as ActRIIB; is a type II receptor containing an extracellular domain (ECD); a transmembrane segment; and a cytoplasmic region that includes the kinase domain. ActRIIB is a receptor for activin A; activin B and inhibin A. Multiple ActRIIB isoforms can also be generated; which bind activin isoforms with different affinities.
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Lyophilized protein should be stored at -20[o]C; though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7[o]C for 2-7 days. Aliquots of reconstituted samples are stable at -20[o]C for 3 months.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
