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Proteins and Peptides

Recombinant Human Thimet Oligopeptidase/THOP1 (C-6His)

Product Sizes
10 µg
£612.00
32-7157-10UG
50 µg
£919.00
32-7157-50UG
About this Product
SKU:
32-7157
Extra Details:
Source: E.coli. MW :80kD. Recombinant Human Thimet Oligopeptidase is produced by our E.coli expression system and the target gene encoding Lys2-Cys689 is expressed with a 6His tag at the C-terminus. Thimet Oligopeptidase (THOP1) belongs to the peptidase M3 family which includes neurolysin and mitochondrial intermediate peptidase. THOP1 is located in Cytoplasm. THOP1 is widely expressed in human tissues and can detected in different subcellular locations. THOP1 is preferential cleavage for bonds with hydrophobic residues at P1; P2 and P3' and a small residue at P1' in substrates of 5 to 15 residues. THOP1 is involved in the metabolism of neuropeptides under 20 amino acid residues and degradation of cytoplasmic peptide. In addition; THOP1 also can degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.
Shipping Conditions:
Dry Ice
Storage Conditions:
Store at -20[o]C; stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins