GCK Human; Active
Product Sizes
1 µg
£452.00
32-6979-1UG
5 µg
£528.00
32-6979-5UG
About this Product
- SKU:
- 32-6979
- Additional Names:
- Glucokinase; Glucokinase (Hexokinase 4); Hexokinase Type IV; HK IV; HK4; Maturity Onset Diabetes of The Young 2; ATP:D-Hexose 6-Phosphotransferase; Hexokinase D; Pancreatic Isozyme; Hexokinase-4; Hexokinase-D; Hexokinase 4.
- Extra Details:
- Source: Escherichia Coli.Sterile filtered colorless solution.GCK is an enzyme that expedite the formation of glucose-6-phosphate for glucose by phosphorylation. Humans and other vertebrates have GCK in the cells of the pancreas and liver. In both organs; the enzyme has an important role in carbohydrate metabolism regulation by sensing sugar levels and acting according to the change in glucose levels; that can rise after a meal or fall during fasting. Mutations in the gene that codes for this enzyme can cause hypoglycemia or diabetes. .GCK Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 485 amino acids (1-465 a.a) and having a molecular mass of 54.3kDa. GCK is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
- Purification:
- Greater than 95% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
