BRAF Human
Product Sizes
5 µg
£452.00
32-6957-5UG
20 µg
£528.00
32-6957-20UG
About this Product
- SKU:
- 32-6957
- Additional Names:
- Proto-Oncogene B-Raf; BRAF1; RAFB1; NS7; EC 2.7.11.1; B-RAF1; P94.
- Extra Details:
- Source: Escherichia Coli.Sterile Filtered colorless solution.B-Raf Proto-Oncogene; also known as BRAF is a member of the raf/mil family of serine/threonine protein kinases. BRAF participates in regulating the MAP kinase/ERKs signaling pathway; which eventually have an effect on cell division; differentiation; and secretion. Mutations in BRAF have been associated with cardiofaciocutaneous syndrome; which is a disease characterized by heart defects; mental retardation and a distinctive facial appearance. In addition; mutations in BRAF have also been associated with different cancers; including non-Hodgkin lymphoma; colorectal cancer; malignant melanoma; thyroid carcinoma; non-small cell lung carcinoma; as well as adenocarcinoma of lung. BRAF Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 360 amino acids (432-766a.a) and having a molecular mass of 40.6kDa. BRAF is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
- Purification:
- Greater than 80.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
