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Antibodies

TIMP2 Human; Sf9

Product Sizes
1 µg
£452.00
32-6925-1UG
5 µg
£528.00
32-6925-5UG
About this Product
SKU:
32-6925
Additional Names:
TIMP Metallopeptidase Inhibitor 2; Tissue Inhibitor Of Metalloproteinases 2; CSC-21K; Tissue Inhibitor Of Metalloproteinase 2; TIMP-2; DDC8; Metalloproteinase inhibitor 2.
Extra Details:
Source: Sf9; Baculovirus cells.Sterile Filtered clear solution.TIMP2 belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases; a group of peptidases that take part in degradation of the extracellular matrix. Besides having an inhibitory role against metalloproteinases; the encoded protein has a exclusive part among TIMP family members in its capability to directly suppress the proliferation of endothelial cells. Consequently; the encoded protein is crucial to the conservation of tissue homeostasis by suppressing the production of quiescent tissues as an answer to angiogenic factors; and by inhibiting protease activity in tissues undergoing renovation of the extracellular matrix.TIMP2 produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 200 amino acids (27-220a.a.) and having a molecular mass of 22.5kDa. (Molecular size on SDS-PAGE will appear at approximately 18-28kDa). TIMP2 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Purification:
Greater than 95.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks.  Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody