PPM1D Human
Product Sizes
2 µg
£452.00
32-6893-2UG
10 µg
£528.00
32-6893-10UG
About this Product
- SKU:
- 32-6893
- Additional Names:
- Protein phosphatase 1D magnesium-dependent; delta isoform; PPM1D; Protein Phosphatase 1D; PP2C-DELTA; WIP1.
- Extra Details:
- Source: Escherichia Coli.Sterile Filtered clear solution.Protein Phosphatase 1D (PPM1D) belongs to the PP2C family of Ser/Thr protein phosphatases whose members are negative regulators of cell stress response pathways. PPM1D is induced by tumor suppressor protein TP53/p53 in response to multiple environmental stresses. PPM1D is a negative regulator of the activity of p38 MAP kinase through which it reduces the phosphorylation of p53 and suppresses p53-mediated transcription and apoptosis. PPM1D is located in a chromosomal area which enlarges in breast cancer.PPM1D Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 299 amino acids (98-375a.a.) and having a molecular mass of 33.2kDa.PPM1D is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
