PON1 Human; HEK
Product Sizes
2 µg
£452.00
32-6889-2UG
10 µg
£528.00
32-6889-10UG
About this Product
- SKU:
- 32-6889
- Additional Names:
- Serum paraoxonase/arylesterase 1; Serum aryldialkylphosphatase 1; Aromatic esterase 1; A-esterase 1 ; Serum aryldialkylphosphatase 1; paraoxonase 1; K-45; ESA; PON; MVCD5
- Extra Details:
- Source: HEK293 Cells.Sterile Filtered colorless solution.Paraoxonase-1 or PON1 is part of the paraoxonase group of proteins. PON1 is an enzyme; responsible to the toxic metabolites of a different of organophosphorus insecticides hydrolyzation. Furthermore; PON1 is a dominant anti-atherosclerotic part of HDL. The enzyme needs PPAR-gamma for activation; leading to synthesis and release of paraoxonase 1 from the liver tissue; resulting in atherosclerosis reduction. PON1 has many qualities for atheroprotective through inflammatory lipid peroxides metabolism. This enzyme can hydrolyze a large number of substrates; for example cyclic carbonates; lactones; nerve gases etc.PON1 Human Recombinant produced in HEK cells is a single; glycosylated; polypeptide chain (16-355 a.a) containing a total of 346 amino acids; having a molecular mass of 39.0kDa. PON1 is fused to a 6 amino acid His-tag at C-terminus;and is purified by proprietary chromatographic techniques.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
