LGMN Mouse
Product Sizes
2 µg
£452.00
32-6835-2UG
10 µg
£528.00
32-6835-10UG
About this Product
- SKU:
- 32-6835
- Additional Names:
- Legumain; Asparaginyl endopeptidase; Protease; cysteine 1.
- Extra Details:
- Source: Sf9; Baculovirus cells.Sterile filtered colorless solution.Legumain; also known as LGMN is a lysosomal cysteine protease which is found in all mouse tissues; however it was mainly abundant in the kidney as well as placenta. LGMN plays an essential role in the endosomal/lysosomal degradation system as the Legumain deficiency causes the accumulation of pro cathepsins B; H & L; another group of lysosomal cysteine proteases. Furthermore; over expression of LGMN in tumors is important for invasion/metastasis.LGMN produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 426 amino acids (18-435a.a.) and having a molecular mass of 48.6kDa. (Molecular size on SDS-PAGE will appear at approximately 40-57kDa). LGMN is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
