HMGCL Human; Sf9
Product Sizes
2 µg
£452.00
32-6803-2UG
10 µg
£528.00
32-6803-10UG
About this Product
- SKU:
- 32-6803
- Additional Names:
- 3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase; 3-Hydroxymethyl-3-Methylglutaryl-Coenzyme A Lyase; 3-Hydroxy-3-Methylglutarate-CoA Lyase; Hydroxymethylglutaricaciduria; HMG-CoA Lyase; EC 4.1.3.4; HL; Mitochondrial 3-Hydroxy-3-Methylglutaryl-CoA Lyase; Hydroxymethylglutaryl-CoA Lyase; Mitochondrial; 3-
- Extra Details:
- Source: Sf9; Baculovirus cells.Sterile Filtered colorless solution.Hydroxymethylglutaryl-CoA lyase (HMGCL) is a mitochondrial matrix protein which is a member of the HMG-CoA lyase family. HMGCL is a homodimer and participates in leucine catabolism and ketogenesis; the hepatic synthesis of ketone bodies which; during fasting; provides a major Source: of energy for the heart; brain and kidney. More precisely; HMGCL catalyzes the final step of these processes; the cleavage of 3-hydroxy-3-methylglutaryl-CoA to acetoacetic acid and acetyl-CoA.HMGCL Human Recombinant produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 305 amino acids (28-325 a.a.) and having a molecular mass of 32.5kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa). HMGCL is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
