DCT Human
Product Sizes
2 µg
£452.00
32-6727-2UG
10 µg
£528.00
32-6727-10UG
About this Product
- SKU:
- 32-6727
- Additional Names:
- L-dopachrome tautomerase (EC:5.3.3.12); DCT; DT; L-dopachrome Delta-isomerase Tyrosinase-related protein 2; TRP-2; TRP2; TYRP2.
- Extra Details:
- Source: Sf9 Insect cells.Sterile Filtered colorless solution.Dopachrome Tautomerase also known as DCT; belongs to the tyrosinase family. DCT takes a significant part in the synthesis of the melanin pigment including tyrosinase (Tyr); tyrosinase-related protein 1 (Tyrp1). Which are highly involved in eumelanin synthesis. The change among the eumelanin and the pheomelanin pathways is assumed to depend on the presence of cysteine. Hence; in the lack of cysteine; dopaquinone; the product of tyrosinase action; is transformed to cyclodopa (leucodopachrome) and afterwards to dopachrome (and DOPA).DCT Human Recombinant produced in Sf9 Insect cell is a single; non-glycosylated polypeptide chain containing 455 amino acids (24-472aa.a) and having a molecular mass of 52.1kDa (Migrates at 50-70kDa on SDS-PAGE under reducing conditions). DCT is fused to a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
