CTSL Mouse
Product Sizes
1 µg
£452.00
32-6712-1UG
5 µg
£528.00
32-6712-5UG
About this Product
- SKU:
- 32-6712
- Additional Names:
- Cathepsin L1; Cathepsin L; Major excreted protein; MEP; p39 cysteine proteinase.
- Extra Details:
- Source: Sf9; Baculovirus cells.Sterile filtered colorless solution.Cathepsin-L also known as CTSL is a member of the peptidase C1 family. CTSL; is a dimer composed of disulfide-linked heavy and light chains; both formed from a single protein precursor. Furthermore; CTSL is a lysosomal cysteine proteinase which takes a main part in intracellular protein catabolism. CTSL substrates include collagen and elastin; as well as alpha-1 protease inhibitor; which is the most important controlling element of neutrophil elastase activity. CTSL has been implicated in a number of pathologic processes; including myofibril necrosis in myopathies and in myocardial ischemia; and in the renal tubular response to proteinuria. Multiple alternatively spliced transcript variants have been found for CTSL.CTSL Mouse Recombinant produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 325 amino acids (18-334a.a.) and having a molecular mass of 36.8kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa). CTSL is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
