CTSD Mouse
Product Sizes
1 µg
£452.00
32-6710-1UG
5 µg
£528.00
32-6710-5UG
About this Product
- SKU:
- 32-6710
- Additional Names:
- Ctsd; CatD; CD; Cathepsin D.
- Extra Details:
- Source: Sf9; Baculovirus cells.Sterile Filtered colorless solution.Cathepsin D is synthesized as a 54kDa precursor; which is proteolytically processed to an intermediate 48kDa single chain; which matures into more stable 34kDa and 14kDa two chain form. It is an estrogen-regulated lysosomal protease that has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane; extracellular matrix; and xonnective tissue. Because of its mitogenic and proteolytic activities; it has been implicated as a prognostic marker in many tumor types. Cathepsin D is expressed in epithelial cells as well as in macrophages.CTSD produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 398 amino acids (21-410 a.a.) and having a molecular mass of 44.0kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa). CTSD is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
