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Antibodies

CDC34 Human

Product Sizes
50 µg
£775.00
32-6692-50UG
100 µg
£1030.00
32-6692-100UG
About this Product
SKU:
32-6692
Additional Names:
UB2R1; CDC-34; Ubiquitin-conjugating enzyme E2 R1; Ubiquitin-protein ligase R1; Ubiquitin-conjugating enzyme E2-32 kDa complementing; E2-CDC34; CDC34; EC 6.3.2.19; UBC3; UBE2R1.
Extra Details:
Source: Escherichia Coli. Sterile Filtered colorless solution.CDC34 takes part in the control of cell cycle and DNA replication. Cdc34 in association with different E3 complexes; including SCF; targets many different substrates for ubiquitination and degradation during cell division; signal transduction; and development. Cdc34 substrates that have been characterized include B-Myb; Wee1; MyoD; ATF5; p27Xic1; and p27Kip1. Additionally; substrates such as p21Cip1; E2F; cyclin E; and cyclin D are putative substrates of Cdc34 by virtue of their SCF requirement for proteolysis. Cdc34 is self-associate through a domain in the C-terminus; and is phosphorylated and ubiquitinylated in vivo. CDC34is useful for in vitro ubiquitinylation reactions.Cell Division Cycle 34 Human Recombinant produced in E.Coli is a single; non- glycosylated polypeptide chain containing 236 amino acids and having a molecular mass of 26.7kDa. CDC34 is purified by proprietary chromatographic techniques.
Purification:
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody