ACE2 (18-615) Human
Product Sizes
1 µg
£485.00
32-6630-1UG
5 µg
£727.00
32-6630-5UG
About this Product
- SKU:
- 32-6630
- Additional Names:
- ACE-2 (Angiotensin converting enzyme 2) an enzyme bound to cell membranes in various organs such as intestines arteries ; lungs; heart & kidney. ACE2 an entry receptor of SARS coronaviruses as well as SARS-CoV-2;.The coronavirus spike (S) glycoprotein is a class I viral fusion antigen located on th
- Extra Details:
- Source: CHO CellsSterile Filtered clear solution.ACE-2 (Angiotensin converting enzyme 2) an enzyme bound to cell membranes in various organs such as intestines arteries ; lungs; heart & kidney. ACE2 an entry receptor of SARS coronaviruses as well as SARS-CoV-2;.The coronavirus spike (S) glycoprotein is a class I viral fusion antigen located on the external envelope of the virion that takes part in a critical part in viral infection by identifying host cell receptors and facilitating fusion of the viral and cellular membranes. 2 main domains in coronavirus S1 have been recognized; the N-terminal domain and C-terminal domain. One or the other and/or both S1 domains function as a receptor-binding domain. SARS-CoV + MERS-CoV equally use C-domain to attach their receptors.ACE2 is a type I transmembrane antigen with an extracellular N-terminal domain having the catalytic site and an intracellular C-terminal tail. ACE2 obtains a signal peptide; a transmembrane domain; and a single metalloproteinase active site containing an HEXXH zinc-binding domain. ACE-2 plays a role as a mono-carboxypeptidase which degrades Ang I to produce the nonapeptide Ang 1–9 and Ang II to create the heptapeptide Ang 1–7.The CHO derived ACE2 Human recombinant protein contains the extracellular domain amino acids 18- 615 fused to Fc tag at C-terminal and has a molecular weight of ~130 kDa. ACE2 Protein binds to SARS Coronavirus-2 [ CoV-2019 ] Spike receptor binding domain.
- Purification:
- Protein is >95% pure as determined SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- ACE-2 Human Recombinant Protein is shipped on ice packs. Upon arrival; Store at -20[o]C.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
