TECK Human; His
Product Sizes
5 µg
£452.00
32-6618-5UG
20 µg
£528.00
32-6618-20UG
About this Product
- SKU:
- 32-6618
- Additional Names:
- C-C motif chemokine 25; Small-inducible cytokine A25; Thymus-expressed chemokine; Chemokine TECK; CCL25; SCYA25; TECK; Ckb15; MGC150327.
- Extra Details:
- Source: Escherichia Coli.Filtered colorless solution.CCL25 (Teck) is a novel CC chemokine; which is distantly related (about 20% amino acid sequence identity) to other CC chemokines. The mouse CCL25 cDNA has also been cloned and shown to encode a 144 a.a. protein; which exhibits 49% a.a. sequence identity to the human CCL25. Human and mouse CCL25 expression was shown to be greatly restricted to the thymus and small intestine. While dendritic cells are identified as the Source: of CCL25 production in the thymus; dendritic cells derived from bone marrow do not express CCL25. CCL25 signals through the CCR9 receptor. Teck is possibly involved in T-cell development. Recombinant human and mouse Teck were shown to be chemotactic for activated macrophages; dendritic cells and thymocytes. The recombinant protein demonstrates chemotactic activity on thymocytes; macrophages; THP-1 cells; and dendritic cells but is inactive on peripheral blood lymphocytes and neutrophils.TECK Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 152 amino acids (24-150 a.a.) and having a molecular mass of 16.8kDa.TECK is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
