TARC Macaque
Product Sizes
50 µg
£775.00
32-6617-50UG
100 µg
£1030.00
32-6617-100UG
About this Product
- SKU:
- 32-6617
- Additional Names:
- C-C motif chemokine 17; Small-inducible cytokine A17; Thymus and activation-regulated chemokine; CC chemokine TARC; ABCD-2; CCL17; CCL-17; SCYA17; TARC; A-152E5.3; MGC138271; MGC138273.
- Extra Details:
- Source: Escherichia Coli.Sterile Filtered White lyophilized (freeze-dried) powder.TARC cDNA encodes a 94 amino acid precursor protein with a 23 amino acid residue signal peptide that is cleaved off to generate the 71 amino acid residue mature secreted protein. Along with CC chemokine family members; CCL-17 has approximately 24-29% amino acid sequence identity with RANTES; MIP-1a; MIP-1b; MCP-1; MCP-2; MCP-3 and I-309. TARC is expressed in thymus; and at a lower level in the lung; colon; and small intestine. TARC is in addition transiently expressed in stimulated peripheral blood mononuclear cells. Recombinant TARC has been shown to be chemotactic for T cell lines but not monocytes or neutrophils. CCL-17 is a specific functional ligand for CCR4; a receptor that is selectively expressed on T cells. CCL17 is one of a few Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. CCL17 shows chemotactic activity for T lymphocytes; but not monocytes or granulocytes. CCL17 binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.Thymus and Activation Regulated Chemokine (CCL17) Rhesus Macaque Recombinant produced in E.Coli is a non-glycosylated polypeptide chain containing 71 amino acid and having a molecular mass of approximately 8.1kDa.TRAC is purified by proprietary chromatographic techniques.
- Purification:
- Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized TRAC although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution Thymus and Activation Regulated Chemokine Rhesus Macaque should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
