MCP 2 Canine
Product Sizes
2 µg
£452.00
32-6610-2UG
10 µg
£528.00
32-6610-10UG
About this Product
- SKU:
- 32-6610
- Additional Names:
- C-C motif chemokine 8; Monocyte chemoattractant protein 2; Monocyte chemotactic protein 2; MCP-2; Small-inducible cytokine A8; CCL8; MCP2.
- Extra Details:
- Source: Escherichia Coli.Sterile Filtered White lyophilized (freeze-dried) powder.Chemokine (C-C motif) ligand 8 (CCL8) is a small cytokine belonging to the CC chemokine family that was once called monocyte chemotactic protein-2 (MCP-2). The CCL8 protein is produced as a precursor containing 109 amino acids; which is cleaved to produce mature CCL8 containing 75 amino acids. The gene for CCL8 is encoded by 3 exons and is located within a large cluster of CC chemokines on chromosome 17q11.2 in humans. MCP-2 is chemotactic for and activates a many different immune cells; including mast cells; eosinophils and basophils; (that are implicated in allergic responses); and monocytes; T cells; and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors called chemokine receptors. These receptors include CCR1; CCR2B and CCR5.MCP2 Canine Recombinant produced in E.coli is a single; non-glycosylated; polypeptide chain containing 76 amino acids and having a molecular mass of 8.8kDa.The CCL8 is purified by proprietary chromatographic techniques.
- Purification:
- Greater than 98.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized MCP-2 although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution CCL8 should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
