BCA1 Macaque
Product Sizes
50 µg
£775.00
32-6601-50UG
100 µg
£1030.00
32-6601-100UG
About this Product
- SKU:
- 32-6601
- Additional Names:
- C-X-C motif chemokine 13; Small-inducible cytokine B13; B lymphocyte chemoattractant; CXC chemokine BLC; CXCL13; BCA1; BCA-1; CXCL-13; B cell Attracting Chemokine-1; BLC; ANGIE; BLR1L; SCYB13; ANGIE2.
- Extra Details:
- Source: Escherichia Coli.Sterile Filtered White lyophilized (freeze-dried) powder.BCA-1 is a CXC chemokine that is highly expressed in thesecondary lymphoid organs; such as follicles of the spleen; lymph nodes; and Peyer's patches. CXCL13 promotes the migration of B lymphocytes (compared to T cells and macrophages); by stimulating calcium influx into; and chemotaxis of; cells expressing Burkitt's lymphoma receptor 1 (BLR1). BCA1 therefore function in the homing of B lymphocytes to follicles. Human BCA-1 shares a 64% amino acid sequence similarity with the mouse protein and 23 - 34% amino acid sequence identity with other known CXC chemokines. Recombinant or chemically synthesized BCA1 is a potent chemoattractant for B lymphocytes but not T lymphocytes; monocytes or neutrophils. BLR1; a G protein-coupled receptor originally isolated from Burkitt’s lymphoma cells; has now been shown to be the specific receptor for BCA1. Among cells of the hematopoietic lineages; the expression of BLR-1; now designated CXCR-5; is restricted to B lymphocytes and a subpopulation of T helper memory cells.BCA-1/ BLC (CXCL13) Rhesus Macaque Recombinant produced in E.Coli is a non-glycosylated polypeptide chain containing 87 amino acid and having a molecular mass of approximately 10.3kDa.BCA1 is purified by proprietary chromatographic techniques.
- Purification:
- Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized BCA1 although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution BCA-1/ BLC (CXCL13) Rhesus Macaque should be stored at 4[o]C between 2-7 days and for future use below -18[o]C. Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
