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Antibodies

VEGF Mouse (121 a.a.); Yeast

Product Sizes
100 µg
£1255.00
32-6593-100UG
250 µg
£1545.00
32-6593-250UG
About this Product
SKU:
32-6593
Additional Names:
Vascular endothelial growth factor A; VEGF-A; Vascular permeability factor; VPF; VEGF; MGC70609.
Extra Details:
Source: Saccharomyces cerevisiae Sterile Filtered White lyophilized (freeze-dried) powder. Vascular endothelial growth factor is an important signaling protein involved in both angiogenesis and vasculogenesis.VEGF activity has been mostly studied on cells of the vascular endothelium; although it does have effects on a number of other cell types (e.g. stimulation monocyte/macrophage migration; neurons; cancer cells; kidney epithelial cells ).VEGF mediates increased vascular permeability; induces angiogenesis; vasculogenesis and endothelial cell growth; promotes cell migration; and inhibits apoptosis. In vitro; VEGF has been shown to stimulate endothelial cell mitogenesis and cell migration. VEGF is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor.Elevated levels of VEGF is linked to POEMS syndrome; also known as Crow-Fukase syndrome. Mutations in VEGF have been associated with proliferative and nonproliferative diabetic retinopathy. Vascular Endothelial Growth Factor (121 a.a.) Mouse Recombinant produced in yeast is a disulfide-linked homodimer consisting of 2x121 amino acid polypeptide chains; having a molecular mass of approximately 20.7kDa each.VEGF (121 a.a.) is purified by proprietary chromatographic techniques.
Purification:
Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Lyophilized VEGF (121 a.a.) although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution Vascular Endothelial Growth Factor (121 a.a.) should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.Please prevent freeze-thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody