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Antibodies

TRAIL Human (114-281 a.a.); Active

Product Sizes
2 µg
£452.00
32-6589-2UG
10 µg
£528.00
32-6589-10UG
About this Product
SKU:
32-6589
Additional Names:
Tumor necrosis factor ligand superfamily member 10; TNF-related apoptosis-inducing ligand; Protein TRAIL; Apo-2 ligand; Apo-2L; CD253 antigen; TL2; APO2L; TNFSF10.
Extra Details:
Source: Escherichia Coli.Sterile Filtered colorless liquid.TNF-related apoptosis-inducing ligand (TRAIL) is a ligand molecule which induces apoptosis. It is a type II transmembrane protein with homology to other members of the tumor necrosis factor family.In humans; the gene that encodes for TRAIL is located at chromosome 3q26.TRAIL binds to the death receptors; DR4 and DR5. The process of apoptosis is caspase-8-dependent. This protein preferentially induces apoptosis in transformed and tumor cells; but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues.Soluble TNF-related apoptosis-inducing ligand Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 169 amino acids (114-281) and having a molecular mass of 19.6 kDa. The sTRAIL is purified by proprietary chromatographic techniques.
Purification:
Greater than 95.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody