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Antibodies

TNFRSF10A Human

Product Sizes
2 µg
£452.00
32-6572-2UG
10 µg
£528.00
32-6572-10UG
About this Product
SKU:
32-6572
Additional Names:
TNFRSF10A; TNF Receptor Superfamily Member 10a; Tumor Necrosis Factor Receptor Superfamily; Member 10a; TNF-Related Apoptosis-Inducing Ligand Receptor 1; Death Receptor 4; TRAIL Receptor 1; TRAIL-R1; TRAILR1; APO2; DR4; Tumor Necrosis Factor Receptor Superfamily Member 10a Variant 2; Tumor Necrosis
Extra Details:
Source: Sf9; Baculovirus cells.Sterile Filtered colorless solution.Human TNFRSF10A is a type 1 transmembrane protein in the TNF R superfamily. TNFRSF10A is not expressed in rodents. The trimeric ligand Trail binds TNFRSF10A and induces apoptosis; and recombinant; soluble forms of the receptor inhibit Trail-induced apoptosis. TNFRSF10A is expressed generally in damaged; infected; and malignant cells. TNFRSF10A functions in immune surveillance; inducing apoptosis in cancer cells but not normal cells.TNFRSF10A produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 224 amino acids (24-239a.a.) and having a molecular mass of 23.9kDa. (Molecular size on SDS-PAGE will appear at approximately 18-28kDa). TNFRSF10A is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Purification:
Greater than 90.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.  For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).  Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody