TNFSF8 Human; Sf9
Product Sizes
1 µg
£452.00
32-6568-1UG
5 µg
£528.00
32-6568-5UG
About this Product
- SKU:
- 32-6568
- Additional Names:
- Tumor Necrosis Factor Superfamily Member 8; Tumor Necrosis Factor (Ligand) Superfamily; Member 8; CD153 Antigen; CD30 Ligand; CD30LG; CD30-L; CD30L; Tumor Necrosis Factor (Ligand) Superfamily Member 8; Tumor Necrosis Factor Ligand 3A; CD30 Antigen Ligand; TNLG3A; CD153; Tumor necrosis factor ligand
- Extra Details:
- Source: Sf9; Baculovirus cells.Sterile filtered colorless solution.CD30 Ligand (TNFSF8) is a cytokine which is a member of the tumor necrosis factor (TNF) ligand family. The TNFSF8 cytokine is a ligand for TNFRSF8/CD30; which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The employment of the TNFSF8 cytokine expressed on B cell surface has an inhibitory role in modulating Ig class switch. TNFSF8 enhances cell proliferation of some lymphoma cell lines; while inducing cell death and reducing cell proliferation of other lymphoma cell lines. The pleiotropic biological activities of the TNFSF8 cytokine on different CD30+ lymphoma cell lines has a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas.TNFSF8 produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 181 amino acids (63-234a.a.) and having a molecular mass of 20.7kDa (Molecular size on SDS-PAGE will appear at approximately 18-40kDa). TNFSF8 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Purification:
- Greater than 85% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
