Leptin Human; N82K PEG
Product Sizes
20 µg
£452.00
32-6483-20UG
100 µg
£528.00
32-6483-100UG
About this Product
- SKU:
- 32-6483
- Additional Names:
- OB Protein; Obesity Protein; OBS; Obesity factor.
- Extra Details:
- Source: Escherichia Coli.Sterile Filtered White lyophilized (freeze-dried) powder.Leptin takes an important part in the regulation of energy balance and body weight control.After entering the circulation; Leptin binds LEPRwhich results in the activation of several major signalling pathways. In the hypothalamus Leptin acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption and also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery; increases basal metabolism; regulates pancreatic beta-cell function and insulin secretion and affects innate and adaptive immunity.Pegylated Leptin N82K Human Recombinant produced in E.Coli is a single non-glycosilated polypeptide chain containing 146 amino acids; an additional Ala at N-terminus and one molecule of PEG 20 kDa at its N-terminus acids and having a molecular weight of 35.6kDa. However due to enlarged hydrodymanic volume it runs on the SDS-PAGE as 48 kDa protein and in gel-filtration on Superdex 200 as over 200 kDa protein. Pegylated Leptin N82K Human Recombinant was purified by proprietary chromatographic techniques.
- Purification:
- Greater than 99.0% as determined by:(a) Gel filtration analysis.(b) Analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized Pegylated Leptin N82K although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution Pegylated Leptin N82K should be stored at 4[o]C between 2-7 days and for future use below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
