IL 33 Rat; His
Product Sizes
5 µg
£452.00
32-6476-5UG
20 µg
£528.00
32-6476-20UG
About this Product
- SKU:
- 32-6476
- Additional Names:
- Interleukin-33; IL-33.
- Extra Details:
- Source: Escherichia Coli.Sterile Filtered colorless solution.nterleukin 33 (IL-33) is a 32kDa proinflammatory cytokine that may also regulate gene transcription in producer cells. IL-33 is structurally related to IL-1; which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1); which is known also as ST2. Binding of IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo; IL-33 induces expression of IL-4; IL-5; IL-13 and leads to severe pathological changes in mucosal organs and in vitro; it can be divided to N-terminal fragment of 12kDa and C-terminal fragment of 18kDa by cleavage of caspase-1.IL 33 Rat Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 179 amino acids (109-264 a.a) and having a molecular mass of 19.8kDa.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
