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Antibodies

IL18RAP Human

Product Sizes
1 µg
£452.00
32-6464-1UG
5 µg
£528.00
32-6464-5UG
About this Product
SKU:
32-6464
Additional Names:
Interleukin-18 receptor accessory protein; IL-18 receptor accessory protein; IL-18RAcP; Accessory protein-like; AcPL; CD218 antigen-like family member B; CDw218b; IL-1R accessory protein-like; IL-1RAcPL; Interleukin-1 receptor 7; IL-1R-7; IL-1R7; Interleukin-18 receptor accessory protein-like; Inte
Extra Details:
Source: Sf9; Insect cells.Sterile filtered colorless solution.Interleukin-18 receptor accessory protein (IL18RAP); belongs to the IL-1 family of cytokines which holds multiple immunoregulatory functions. It has been found that IL18RAP does not mediate IL18-binding; however; IL18RAP is involved in IL18-dependent signal transduction; which leads to NF-kappa-B and JNK activation. IL18R1 as well as IL18RAP polymorphisms have been linked with the following diseases: schizophrenia; HSV1 seropositivity and atopic asthma.IL18RAP produced in Sf9 Insect cells is a single; glycosylated polypeptide chain containing 576 amino acids (20-356 a.a.) and having a molecular mass of 65.4kDa (Molecular size on SDS-PAGE will appear at approximately 70-100kDa).IL18RAP is expressed with an 239 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Purification:
Greater than 90.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody