IGFBP4 Sf9; Human
Product Sizes
2 µg
£452.00
32-6401-2UG
10 µg
£528.00
32-6401-10UG
About this Product
- SKU:
- 32-6401
- Additional Names:
- Insulin-like growth factor-binding protein 4; IBP-4; IGF-binding protein 4; IGFBP-4; IGFBP4; IBP4; BP-4; HT29-IGFBP.
- Extra Details:
- Source: Sf9; Insect cells.Sterile Filtered White lyophilized (freeze-dried) powder.Insulin-like growth factor-binding protein 4 (IGFBP-4) is a part of the insulin-like growth factor binding protein (IGFBP) family. IGFBP4 includes an IGFBP domain and a thyroglobulin type-I domain. IGFBP4 binds both insulin-like growth factors (IGFs) I and II. IGFBP-4 circulates in the plasma in both glycosylated and non-glycosylated forms. IGFBPs can either inhibit or enhance the biological activities of IGF; or act in an IGF independent manner. IGFBP-4 is consistently inhibits several cancer cells in vivo and in vitro; suggesting that it may function as an apoptotic factor. IGFBP4 is produced by all colon cancer cells. Binding of IGFBP-4 prolongs the half-life of the IGFs and changes their interaction with cell surface receptors.Insulin Like Growth Factor Binding Protein-4 Human Recombinant produced in Sf9 Insect cells is a single; glycosylated polypeptide chain containing 237 amino acids and having a molecular mass of 30kDa. The IGFBP4 is purified by proprietary chromatographic techniques.
- Purification:
- Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized IGFBP4 although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution Insulin Like Growth Factor Binding Protein-4 should be stored at 4[o]C between 2-7 days and for future use below -18[o]C. Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
