FGF12 Human
Product Sizes
2 µg
£452.00
32-6349-2UG
10 µg
£528.00
32-6349-10UG
About this Product
- SKU:
- 32-6349
- Additional Names:
- FGF-12; FGF12; FGF12B; FHF1; Fibroblast growth factor 12; Fibroblast growth factor homologous factor 1; FHF-1; Myocyte-activating factor.
- Extra Details:
- Source: Escherichia Coli. Sterile Filtered White lyophilized (freeze-dried) powder.FGF12 is part of the Fibroblast Growth Factor (FGF) family which has a vast mitogenic and cell survival functions; and play a role in a range of biological activities; among them are embryonic development; cell growth; morphogenesis; tissue repair; tumor growth; and invasion. FGF-12 doesn’t obtain the N-terminal signal sequence present in the majority of the FGF family members; but it contains clusters of basic residues that act as a nuclear localization signal. When transfected into mammalian cells; FGF12 accumulated in the nucleus; but was not secreted. FGF12 is involved in nervous system development and function. FGF12 binds to IB2 (islet brain-2); a cellular kinase scaffold; and voltage gated sodium channels and is also involved in intracellular signalling and ion exchange.Fibroblast Growth Factor 12 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 181 amino acids and having a molecular mass of 20.5kDa. The FGF12 is purified by proprietary chromatographic techniques.
- Purification:
- Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized FGF12 although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution Fibroblast Growth Factor 12 should be stored at 4[o]C between 2-7 days and for future use below -18[o]C. Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
