EPOR Human; Active
Product Sizes
2 µg
£452.00
32-6343-2UG
10 µg
£528.00
32-6343-10UG
About this Product
- SKU:
- 32-6343
- Additional Names:
- EPO-R; EPOR; Erythropoietin Receptor.
- Extra Details:
- Source: Sf9; Baculovirus cells.Sterile Filtered clear solution.Erythropoietin receptor; also known as EPOR arbitrates erythropoietin-induced erythroblast proliferation as well as differentiation. During EPO binding; EPOR activates Jak2 tyrosine kinase which activates various intracellular pathways including: Ras/MAP kinase; phosphatidylinositol 3-kinase and STAT transcription factors. Furthermore; stimulated EPOR has a function in erythroid cell survival. Mutations in EPOR may possibly produce erythroleukemia and familial erythrocytosis. In addition; dysregulation of EPOR can affect on the growth of selected tumors.EPOR produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 232 amino acids (25-250a.a.) and having a molecular mass of 25.6kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa).EPOR is expressed with a 6 amino acid His-tag at C-Terminus and purified by proprietary chromatographic techniques.
- Purification:
- Greater than 95.0% as determined by analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
