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Antibodies

EREG Human; His

Product Sizes
5 µg
£452.00
32-6339-5UG
25 µg
£528.00
32-6339-25UG
About this Product
SKU:
32-6339
Additional Names:
Epiregulin; Proepiregulin; ER; ERP.
Extra Details:
Source: Escherichia Coli.Sterile Filtered colorless solution.Epiregulin is part of the EGF family. Epiregulin functions as a ligand of EGFR; as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors.Epiregulin is expressed mostly in the placenta and peripheral blood leukocytes and in specific carcinomas of the bladder; lung; kidney and colon. Epiregulin stimulates the proliferation of keratinocytes; hepatocytes; fibroblasts and vascular smooth muscle cells. Epiregulin inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein; which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence.EREG Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 69 amino acids (63-108 a.a) and having a molecular mass of 7.7kDa. EREG is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Purification:
Greater than 80.0% as determined by SDS-PAGE
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody