BMP13 Human
Product Sizes
10 µg
£452.00
32-6314-10UG
50 µg
£528.00
32-6314-50UG
About this Product
- SKU:
- 32-6314
- Additional Names:
- Growth Differentiation Factor 6; Growth/Differentiation Factor 16; Bone Morphogenetic Protein 13; BMP-13; BMP13; GDF-6; Klippel-Feil Malformation; Segmentation Syndrome 1; Klip-Feil Malformation; Klippel-Feil Syndrome; MCOPCB6; SCDO4; CDMP2; LCA17; MCOP4; GDF16; KFS1; KFSL; SGM1; KFM; KFS; GDF6.
- Extra Details:
- Source: Escherichia Coli. Sterile Filtered White lyophilized (freeze-dried) powder. Growth/differentiation factors (GDF1-GDF15) belong to the BMP family of TGF-beta superfamily proteins. These factors are produced as inactive preproproteins which are subsequently cleaved and assembled into active secreted homodimers. BMP13 is a growth factor which controls proliferation and cellular differentiation in the retina and bone formation. BMP13 has a central role in regulating apoptosis during retinal development. GDF proteins are vital during embryonic development; particularly in the skeletal; nervous; and muscular systems. BMP13 gene mutations result in colobomata; which are congenital abnormalities in ocular development; and in Klippel-Feil syndrome (KFS); which is a congenital disorder of spinal segmentation. BMP13 Human Recombinant produced in E.coli is a non-glycosylated disulfide linked homodimer containing 2 chains of 120 amino acids and having a molecular mass of 27.1kDa.The BMP-13 is purified by proprietary chromatographic techniques.
- Purification:
- Greater than 95.0% as determined by: (a) Analysis by HPLC. (b) Analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized BMP13 although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution BMP-13 should be stored at 4[o]C between 2-7 days and for future use below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
