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Antibodies

BD14 Mouse

Product Sizes
5 µg
£452.00
32-6306-5UG
20 µg
£528.00
32-6306-20UG
About this Product
SKU:
32-6306
Additional Names:
Beta-defensin 14; BD-14; mBD-14; Defensin; beta 14; Defb14.
Extra Details:
Source: Escherichia Coli.Sterile Filtered White lyophilized (freeze-dried) powder.Alpha and Beta Defensins are cationic peptides with antimicrobial activity against Gram-negative and Gram-positive bacteria; fungi and enveloped viruses. These 2-6kDa proteins have vital roles in innate immune system. Mammalian Defensins are classified into alpha; beta and theta categories; based on their size and pattern of disulfide bonding. Beta-Defensins contain a six-cysteine motif which forms 3 intra-molecular disulfide bonds. Since beta-defensins are cationic peptides; they can therefore interact with the membrane of invading microbes; which are negative due to lipopolysaccharides (LPS) and lipoteichoic acid (LTA) found in the cell membrane. In addition; they can affect the stability of the membrane.Beta Defensin-14 Mouse Recombinant produced in E.coli is a single; non-glycosylated; polypeptide chain containing 45 amino acids and having a molecular mass of 5.2kDa.The BD14 is purified by proprietary chromatographic techniques.
Purification:
Greater than 96.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Lyophilized Mouse BD14 although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution BD-14 should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody