ANGPT2 Human
Product Sizes
2 µg
£452.00
32-6296-2UG
10 µg
£528.00
32-6296-10UG
About this Product
- SKU:
- 32-6296
- Additional Names:
- Angiopoietin-2; Angiopoietin2; ANGPT2; ANG2; ANG-2; ANGPT-2.
- Extra Details:
- Source: Chinese Hamster Ovary Cells (CHO).Sterile filtered colorless solution.ANGPT2 aka Angiopoietin-2 competes for binding to the TIE2 receptor and blocks angiopoietin-1 aka ANGPT1 induced TIE2 autophosphorylation during vasculogenesis. ANGPT-2 is a naturally occurring antagonist of ANGPT-1. ANGPT2 induces tyrosine phosphorylation of TEK/TIE2 in the lack of Angiopoietin-2. In the deficiency of VEGF an angiogenic inducer; ANGPT-2 induces endothelial cell apoptosis resulting in vascular regression. ANGPT2 along with VEGF enable endothelial cell migration and proliferation; resulting in permissive angiogenic signal.ANGPT2 produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology is a single; polypeptide chain (19-496 a.a.) and fused to a 6 aa His Tag at C-terminus containing a total of 484 amino acids and having a molecular mass of 55.7kDa.ANGPT2 shows multiple bands between 50-100kDa on SDS-PAGE; reducing conditions and purified by proprietary chromatographic techniques.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
