Acrp30 Human; Sf9
Product Sizes
1 µg
£452.00
32-6293-1UG
5 µg
£528.00
32-6293-5UG
About this Product
- SKU:
- 32-6293
- Additional Names:
- Adiponectin; C1Q And Collagen Domain Containing; Adipose Most Abundant Gene Transcript 1 Protein; Adipocyte Complement-Related 30 KDa Protein; 30 KDa Adipocyte Complement-Related Protein; ACRP30; APM-1; GBP28; ACDC; APM1; Adipocyte; C1q And Collagen Domain-Containing Protein; Adipocyte; C1Q And Col
- Extra Details:
- Source: Sf9; Baculovirus cells.Sterile Filtered clear solution.The adipose tissue exclusively expresses and secretes Adiponectin (Acrp30). Acrp30 is involved in various physiological processes such as energy homeostasis; insulin sensitivity; hormonal processes; fatty acid metabolism and obesity. Adiponectin circulates in the plasma. Decreased levels of Adiponectin are associated with insulin resistance and hyperinsulinemia; as seen in people with obesity insulin resistance; and diabetes type 2; whose plasma levels of adiponectin are reduced.The modular structure of Acrp30 is comprised of N-terminal collagenous domain followed by a C-terminal globular domain.Acrp30 also acts as a significant negative regulator in hematopoiesis and immune systems; it may be involved in ending inflammatory responses through its inhibitory functions. Adiponectin inhibits endothelial NF-kappa-b signaling through a cAMP-dependent pathway; it also inhibits TNF-alpha- induced expression of endothelial adhesion molecules.Acrp30 Human Recombinant produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 146 amino acids (106-242a.a.) and having a molecular mass of 16.9kDa. (Molecular size on SDS-PAGE will appear at approximately 13.5-18kDa). Acrp30 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Purification:
- Greater than 95% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
