Recombinant HTLV-1 Mosaic
Product Sizes
0.5 mg
£1030.00
32-5610-0.5MG
About this Product
- SKU:
- 32-5610
- Extra Details:
- Source : The E.Coli derived recombinant mosaic protein contains the gp21 and gp46 immunodominant regions; 374-400 amino acids and 190-207 amino acids; the MW is 42kDa. The protein is fused with GST at N-terminus. Human T-lymphotropic virus (HTLV) is a human; single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4; IL-5; IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies).
- Purification:
- HTLV-1 Mosaic protein is >95% pure as determined by 10% PAGE (coomassie staining) and RP-HPLC.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- HTLV-1 Mosaic although stable at 4[o]C for 1 week; should be stored below -18[o]C. Please prevent freeze thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
