Recombinant HIV-1 p31 Integrase
Product Sizes
0.5 mg
£1030.00
32-5584-0.5MG
About this Product
- SKU:
- 32-5584
- Extra Details:
- Source : Escherichia Coli. The E.coli derived recombinant protein is a non-glycosylated polypeptide chain; containing the HIV-1 immunodominant regions from the p31 protein (integrase) 9-289 amino acids; fused with six histidines at N-terminus. Integrase is an enzyme produced by the HIV which enables its genetic material to be integrated into the DNA of the infected cell and is a key component in the pre-integration complex. HIV integrase contains 3 domains; an N-terminal HH-CC zinc fingerdomainwhich is partially responsible for multimerization; a central catalytic domain and a C-terminal domain. Both Central catalytic domain and C-terminal domains have been shown to bind both viral and cellular DNA. No crystal structure data exists with Integrase bound to its DNA substrates. HIV-1 integrase functions as a dimeror a tetramer. Additionally; several host cellular proteins interact with integrase and may facilitate the integration process.
- Purification:
- Greater than 95.0% as determined by HPLC analysis and SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- HIV-1 Integrase p31 although stable at 4[o]C for 1 week; should be stored below -18[o]C. Please prevent freeze thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
