Recombinant Human Hepatitis B Virus x Interacting Protein
Product Sizes
20 µg
£528.00
32-5502-20UG
About this Product
- SKU:
- 32-5502
- Additional Names:
- Ragulator complex protein LAMTOR5||Hepatitis B virus X-interacting protein||HBV X-interacting protein||HBX-interacting protein||Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5||LAMTOR5||HBXIP||XIP.
- Extra Details:
- Source : Escherichia Coli. HBXIP Human Recombinant produced in E. coli is a single polypeptide chain containing 197 amino acids (aa 1-173) and having a molecular mass of 20.7kDa.HBXIP is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Hepatitis B virus x interacting protein (HBXIP) forms a complex with the C-terminus of hepatitis B virus X (HBX) protein. HBXIP negatively regulates HBX activity and changes the replicative life cycle of the virus. Furthermore; HBXIP is involved in bipolar spindle formation and regulates centrosome dynamics and cytokinesis in cells; possibly due to interaction with Dynein light chain. HBXIP is highly expressed in the skeletal and cardiac muscle; followed by pancreas; kidney; liver; brain; placenta and lung. HBXIP has elevated levels in both cancerous and non-cancerous liver tissue of patients with chronic HBV infection compared with hepatic tissue without HBV infection.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
