Recombinant HepatitisB Virus Core (1-183)
Product Sizes
0.5 mg
£1030.00
32-5499-0.5MG
About this Product
- SKU:
- 32-5499
- Extra Details:
- Source : The E.Coli derived 18 kDa recombinant protein contains the HBV core ayw immunodominant region; amino acids 1-183. Hepatitis B is one of a few known non-retroviralviruses which employ reverse transcriptionas a part of its replication process. (HIV; a completely unrelated virus; also uses reverse transcription; but it is a retrovirus.) HBV invades the cell by binding to surface receptor and become internalized. The viral core particles then migrate to the hepatocyte nucleus and the partially double-stranded; relaxed circular genomes (RC-DNA) are repaired to form a covalently closed circular DNA (cccDNA); which is the template for viral genomic and sub-genomic RNAs by cellular RNA polymerase II. Of these; the pregenomic RNA (pgRNA is selectively packaged into progeny capsids and is then reverse-transcribed into new RC-DNA. The core can either bud into the endoplasmic reticulum to be enveloped or exported from the cell or recycled back into the genome for conversion to cccDNA.
- Purification:
- HBV Core protein is >95% pure as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- HBV Core protein although stable at 4[o]C for 1 week; should be stored below -18[o]C. Please prevent freeze thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
