Recombinant Shiga Like Toxin-2 Subunit B
Product Sizes
0.5 mg
£1030.00
32-5363-0.5MG
About this Product
- SKU:
- 32-5363
- Extra Details:
- Source : Escherichia Coli. Recombinant Shiga Like Toxin-2 Subunit B from E.Coli O157:H7 produced in E.coli having an Mw of 22kDa.The Shiga Like Toxin 2 protein is fused to a 6xHis tag at its N-terminus and purified by proprietary chromatographic technique. Shiga-like toxin (verotoxin) is a toxin produced by some strains of Escherichia coli. Shiga-like toxin is named for its similarity to the AB5-type Shiga toxin produced by the bacteria Shigella dysenteriae. There are two known types-SLT1 and SLT2. The Shiga-like toxin is linked with hemolytic-uremic syndrome. Shiga-like toxin requires highly specific receptors on the cells' surface in order to attach and enter the cell. Species such as cattle; swine; and deer which do not carry these receptors may harbor toxigenic bacteria without any ill effect; dropping them in their feces; from where they may be distributed to humans. Shiga Like Toxin-2 Subunit B has nontoxic action; it is the functional region which binds to the receptor. Upon binding to the host cell receptor; the Shiga Like Toxin-2 Subunit B forms a pentamer. The Shiga Like Toxin-2 Subunit B can be useful in vaccine study; antibody test and other functional research.
- Purification:
- Protein is >95% pure as determined by 12% PAGE (coomassie staining).
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
