Recombinant Phospholipase A2 P00630 Bee Venom Protein
Product Sizes
0.5 mg
£1030.00
32-5354-0.5MG
About this Product
- SKU:
- 32-5354
- Additional Names:
- Phospholipase A2||Phosphatidylcholine 2-acylhydrolase||Allergen Api m I||Api m 1.
- Extra Details:
- Source : Escherichia Coli. The E.Coli derived recombinant protein contains phospholipase P00630 bee venom protein epitopes; 26-162 amino acids. Bee venom phospholipase A2 (PLA) is the main allergen in the bee sting allergy. Bee venom phospholipase A2 (BV-PLA2) is a hydrolytic enzyme which specifically cleaves the sn-2 acyl bond of phospholipids at the lipid/water interface. BV-PLA2 is a 14-16-kDa glycoprotein; consisting of 134 amino acids and displaying a single carbohydrate side chain at the residue Asn13. It is also held to be responsible for some systemic anaphylactic reactions in bee venom sensitized individuals. BV-PLA2 presents 3 peptide and a glycopeptide T cell epitopes; which are recognized by both allergic and non-allergic bee venom sensitized subjects. PLA is able to elicit both IgE mediated allergy and normal immunity to bee sting which usually is associated with high affinity IgG4 anti-PLA antibodies.
- Purification:
- Protein is >90% pure as determined by 10% SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Phospholipase A2 although stable at 4[o]C for 1 week; should be stored below -18[o]C. Please prevent freeze thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
