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Proteins and Peptides

Recombinant Yeast Thioredoxin

Product Sizes
20 µg
£528.00
32-5263-20UG
About this Product
SKU:
32-5263
Additional Names:
Thioredoxin-1||Thioredoxin I||TR-I||Thioredoxin-2||TRX1||TRX2||YLR043C.
Extra Details:
Source : Escherichia Coli. Thioredoxin Yeast Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain having a molecular mass of 12.6kDa. Thioredoxins are small disulphide-containing redox proteins (within the conserved Cys-Gly-Pro-Cys active site) that have been found in all the kingdoms of living organisms. Thioredoxin contains a single disulfide active site and serves as a general protein disulphide oxidoreductase. Thioredoxins are involved in the first unique step in DNA synthesis. It interacts with a broad range of proteins by a redox mechanism based on reversible oxidation of two cysteine thiol groups to a disulphide; accompanied by the transfer of two electrons and two protons. The net result is the covalent interconversion of a disulphide and a dithiol. It has been suggested that thioredoxin may catalyze the formation of correct disulfides during protein folding because of its ability to act as an efficient oxidoreductant. Trx also provides control over a number of transcription factors affecting cell proliferation and death through a mechanism referred to as redox regulation.
Purification:
Greater than 95.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
TRX although stable at 4[o]C for 3 weeks; should be stored desiccated below -18[o]C. Please prevent freeze thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
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