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Recombinant Human Vacuolar Protein Sorting 4 Homolog B

Product Sizes
10 µg
£528.00
32-5230-10UG
About this Product
SKU:
32-5230
Additional Names:
Vacuolar Protein Sorting 4 Homolog B (S. Cerevisiae)||SKD1||Suppressor Of K+ Transport Defect 1||Cell Migration-Inducing Gene 1 Protein||Suppressor Of K(+) Transport Growth Defect 1;Vacuolar Protein Sorting 4B (Yeast)||SKD1B||PS4-2||Cell Migration-In
Extra Details:
Source : E.coli. VPS4B Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 468 amino acids (1-444 a.a) and having a molecular mass of 51.8kDa. VPS4B is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Vacuolar protein sorting-associated protein 4B (VPS4B) is a member of the AAA (ATPases associated with diverse cellular activities) family. VPS4B is involved in late steps of the endosomal multivesicular bodies (MVB) pathway and recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly; probably in combination with membrane fission. A dominant negative mutant of VPS4B inhibits vacuolar protein sorting and also arrest HIV-1 and MLV budding.
Purification:
Greater than 90% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg