Recombinant Human TSC22 Domain Family; Member 3
Product Sizes
10 µg
£528.00
32-5144-10UG
About this Product
- SKU:
- 32-5144
- Additional Names:
- TSC22 domain family protein 3||DSIP-immunoreactive peptide||Protein DIP||hDIP||Delta sleep-inducing peptide immunoreactor||Glucocorticoid-induced leucine zipper protein||GILZ||TSC-22-like protein||TSC-22-related protein||TSC-22R||TSC22D3||DSIPI||DIP.
- Extra Details:
- Source : Escherichia Coli. TSC22D3 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 157 amino acids (1-134 a.a) and having a molecular mass of 17.2kDa.TSC22D3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. TSC22 domain family protein 3 (TSC22D3) protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity which initiates the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages; TSC22D3 has a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells; TSC22D3 hinders anti-CD3-induced NFKB1 nuclear translocation. In vitro; TSC22D3 curbs AP1 and NFKB1 DNA-binding activities.
- Purification:
- Greater than 85.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
