Recombinant Human Cardiac Troponin-C His
Product Sizes
10 µg
£528.00
32-5135-10UG
About this Product
- SKU:
- 32-5135
- Additional Names:
- Troponin C slow skeletal and cardiac muscles||TN-C||TNNC1||TNNC||TNC||CMD1Z.
- Extra Details:
- Source : E.coli. Troponin-C His Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 181 amino acids (1-161) and having a molecular mass of 20.5 kDa.Intein is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Troponin is a fundamental regulatory protein of striated muscle contraction; and together with tropomyosin; is positioned on the actin filament. Troponin has 3 subunits: TnI- the inhibitor of actomyosin ATPase; TnT- contains the binding site for tropomyosin; and TnC- the protein encoded by the TNNC1 gene. The binding of calcium to TnC stops the inhibitory action of TnI; consequently allowing the interaction of actin with myosin; the hydrolysis of ATP; and the generation of tension. Mutations in the TNNC1 gene are linked to cardiomyopathy dilated type 1Z.
- Purification:
- Greater than 95% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
