Recombinant Human Tripartite Motif Containing 21 (RO52)
Product Sizes
20 µg
£500.00
32-5127-20UG
About this Product
- SKU:
- 32-5127
- Additional Names:
- 52 kDa Ro protein||Sjoegren syndrome type A antigen||SS-A||Ro(SS-A)||52 kDa ribonucleoprotein autoantigen Ro/SS-A||Tripartite motif-containing protein 21||RING finger protein 81||TRIM21||RNF81||RO52||SSA1||SSA||RO-52.
- Extra Details:
- Source : Sf9 insect cells. TRIM21 Human Recombinant produced in SF9 is a glycosylated; polypeptide chain having a calculated molecular mass of 54;922 Dalton. TRIM21 is expressed with a -6x His tag at N-terminus and purified by proprietary chromatographic techniques. TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains; a RING; a B-box type 1 and a B-box type 2; and a coiled-coil region. The 52 kDa Ro protein is part of the RoSSA ribonucleoprotein; which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. Ro/SSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Ribonucleoprotein particle is composed of a single polypeptide and one of four small RNA molecules. The RoSSA is present in all mammalian cells studied but has no known function. At least 2 isoforms are present in nucleated and red blood cells; and tissue specific differences in Ro/SSA proteins were identified.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
