Recombinant Human TP53 Regulated Inhibitor Of Apoptosis 1
Product Sizes
20 µg
£528.00
32-5126-20UG
About this Product
- SKU:
- 32-5126
- Additional Names:
- TP53 Regulated Inhibitor of Apoptosis 1||P53-Inducible Cell-Survival Factor||Mitochondrial Distribution And Morphology 35 Homolog||Protein 15E1.1||MDM35||WF-1||p53CSV||HSPC132.
- Extra Details:
- Source : Escherichia Coli. TRIAP1 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 99 amino acids (1-76 a.a) and having a molecular mass of 11.2kDa.TRIAP1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. TRIAP1 has a p53-binding site in its second exon. TRIAP1 expression is reduced by small interfering RNA enhanced apoptosis; while overexpression of TRIAP1 protects cells from apoptosis triggered by DNA damage. TRIAP1 is highly induced when cells have low levels of genotoxic stresses; but not when DNA damage is severe. TRIAP1 is able to control apoptotic pathways by interacting with Hsp70 which inhibits activity of apoptosis protease activating factor-1.
- Purification:
- "Greater than 90.0% as determined by SDS-PAGE."
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
