Recombinant Human Troponin I Type 2
Product Sizes
10 µg
£528.00
32-5100-10UG
About this Product
- SKU:
- 32-5100
- Additional Names:
- Troponin I fast skeletal muscle||Troponin I fast-twitch isoform||TNNI2||DA2B||FSSV||fsTnI||AMCD2B.
- Extra Details:
- Source : Escherichia Coli. Skeletal isoforms of Troponin I were suggested to be used as markers of acute and chronic skeletal muscle injuries. In skeletal muscles Troponin I is presented by two forms; slow (21.6 kDa) and fast (21.2 kDa) skeletal. The protein (Fast Skeletal Troponin I) migrates on SDS-PAGE to approximately 26.5kDa. TNNI2 is a fast-twitch skeletal muscle protein; belongs to the troponin I gene family; and is part of the troponin complex including troponin T; troponin C and troponin I subunits. The troponin complex; together with tropomyosin; is responsible for the calcium-dependent regulation of striated muscle contraction. TNNI2 is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. Other than muscle tissues; TNNI2 is found in corneal epithelium; cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis; and mammary gland where it functions as a coactivator of estrogen receptor-related receptor alpha. Furthermore; TNNI2 suppresses tumor growth in human ovarian carcinoma. Mutations in the TNNI2 gene cause myopathy and distal arthrogryposis type 2B.
- Purification:
- Greater than 85.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- TNNI2 Human although stable at 10[o]C for 7 days; should be stored below -18[o]C.Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
