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Recombinant Human TNFAIP3 Interacting Protein 1

Product Sizes
5 µg
£528.00
32-5097-5UG
About this Product
SKU:
32-5097
Additional Names:
TNFAIP3-interacting protein 1||HIV-1 Nef-interacting protein||Nef-associated factor 1||Naf1||Nip40-1||Virion-associated nuclear shuttling protein||VAN||hVAN||TNIP1||KIAA0113||NAF1||ABIN-1.
Extra Details:
Source : Escherichia Coli. TNIP1 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 458 amino acids (94-530 a.a.) and having a molecular mass of 51.8kDa. The TNIP1 is purified by proprietary chromatographic techniques. TNFAIP3-interacting protein 1 (TNIP1) interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with a RIP- or TRAF2-mediated transactivation signal. Furthermore; TNIP1 interacts with HIV-1 matrix protein and is packaged into virions and its overexpression can inhibit viral replication. TNIP1 can regulate matrix nuclear localization; both nuclear import of Preintegration complex (PIC) and export of GAG polyprotein and viral genomic RNA during virion production.
Purification:
Greater than 75.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
TNIP1 should be stored desiccated below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg