Recombinant Human Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein
Product Sizes
10 µg
£528.00
32-5092-10UG
About this Product
- SKU:
- 32-5092
- Additional Names:
- Toll-interleukin 1 receptor (TIR) domain containing adaptor protein||adapter protein wyatt||BACTS1||Mal||wyatt||Toll-like receptor adaptor protein||TIR domain-containing adapter protein||MyD88 adapter-like protein.
- Extra Details:
- Source : E.coli. TIRAP Human Recombinant produced in E. coli is a single polypeptide chain containing 244 amino acids (1-221) and having a molecular mass of 26.3 kDa.TIRAP is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Toll-interleukin1 receptor (TIR) domain containing adaptor protein (TIRAP) contains 1 TIR domain. TIRAP is an adapter molecule linked with toll-like receptors. TIRAP is required in TLR2 and TLR4 signaling pathways in the innate immune response. TIRAP activates NF-kappa-B; MAPK1; MAPK3 and JNK; which subsequently results in cytokine secretion and the inflammatory response. TIRAP is highly expressed in the liver; kidney; spleen; skeletal muscle and heart. TIRAP is also found in peripheral blood leukocytes; lung; placenta; small intestine; thymus; colon and brain.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
